Some great productivity tools for your own endeavours. More importantly, some real talk about the mental cost that work takes on you. Some real insights into trying to have steady progress. Not huge burst followed by mental breakdowns.
Technically, it's an excellent talk about systems engineering. That is, looking broadly at systems, how you can significantly simplify and reduce the problem if you're willing to forgo interfaces. With that broad theme in mind, the actual talk ends up being a whirlwind tour through a lot of the VR headset and video/image technologies John was working on at the time. Excellent technical talk as always.